Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening. [version 1; peer review: 2 approved]
Background Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. Platinum/pemetrexed chemotherapy has been used for many years but provides little benefit and, despite recent immunotherapy advances, prognosis remains poor underpinning the need for development of nove...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2025-05-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/14-481/v1 |
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