Artesunate Promotes Bone Remodeling Through TRAF6-Mediated NF-κB Signaling Under Orthodontic Stress in Diabetic Rats

Artesunate Promotes Bone Remodeling Through TRAF6-Mediated NF-κB Signaling Under Orthodontic Stress in Diabetic Rats

Objectives: To determine the effects of artesunate (ART) on bone remodeling in vivo under orthodontic stress in diabetic rats and explore the underlying mechanisms in vitro. Materials and methods: A rat model of type 2 diabetes mellitus with orthodontic tooth movement was established. The rats recei...

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Bibliographic Details
Main Authors: Yuxiang Zhan, Siqin Zhang, Minjie Yang, Yuchen Wang, Jiaquan Li, Xiaolin Nong
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:International Dental Journal
Subjects:
Type 2 diabetes
Orthodontic force
Artesunate
TRAF6
NF-κB
Bone reconstruction
Online Access:http://www.sciencedirect.com/science/article/pii/S0020653925001200
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