PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB–p65/NLRP3 pathway

Objective(s): Asthma is a complex inflammatory disease of the lungs marked by increased infiltration of leukocytes into the airways, which restricts respiratory function. Proliferator-activated receptor-γ coactivator-1 alpha (PGC-1α) has been recognized as an essential immunomodulator and has the po...

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Bibliographic Details
Main Authors: Rui Fang, Yan Cheng, Ping Chen, Jing Hu, Liqi Yang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_25549_487eed30caf841dfa263a143f12225f7.pdf
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