Heterologous biosynthesis of cotylenol and concise synthesis of fusicoccane diterpenoids

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Heterologous biosynthesis of cotylenol and concise synthesis of fusicoccane diterpenoids

A novel strategy for the synthesis of fusicoccane diterpenoids is reported. By harnessing the biosynthetic pathways of brassicicenes and fusicoccins, cotylenol was produced in an engineered Aspergillus oryzae strain. We further achieved the concise synthesis of three fusicoccane diterpenoids, includ...

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Autori principali:	Ye Yuan, Zhenhua Guan, Xue-Jie Zhang, Nanyu Yao, Wenling Yuan, Yonghui Zhang, Ying Ye, Zheng Xiang
Natura:	Articolo
Lingua:	inglese
Pubblicazione:	Beilstein-Institut 2025-07-01
Serie:	Beilstein Journal of Organic Chemistry
Soggetti:	cotylenol fusicoccane diterpenoids heterologous biosynthesis p450 oxidation synthesis
Accesso online:	https://doi.org/10.3762/bjoc.21.111
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

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