Heterologous biosynthesis of cotylenol and concise synthesis of fusicoccane diterpenoids

A novel strategy for the synthesis of fusicoccane diterpenoids is reported. By harnessing the biosynthetic pathways of brassicicenes and fusicoccins, cotylenol was produced in an engineered Aspergillus oryzae strain. We further achieved the concise synthesis of three fusicoccane diterpenoids, includ...

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Auteurs principaux: Ye Yuan, Zhenhua Guan, Xue-Jie Zhang, Nanyu Yao, Wenling Yuan, Yonghui Zhang, Ying Ye, Zheng Xiang
Format: Article
Langue:anglais
Publié: Beilstein-Institut 2025-07-01
Collection:Beilstein Journal of Organic Chemistry
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Accès en ligne:https://doi.org/10.3762/bjoc.21.111
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