The J-shaped association between the ratio of neutrophil counts to prognostic nutritional index and mortality in ICU patients with sepsis: a retrospective study based on the MIMIC database

The J-shaped association between the ratio of neutrophil counts to prognostic nutritional index and mortality in ICU patients with sepsis: a retrospective study based on the MIMIC database

BackgroundThe ICU faces persistent challenges with sepsis, marked by systemic inflammation and metabolic disruptions, often leading to poor outcomes. Despite advances, reliable biomarkers for predicting sepsis outcomes are needed. This study introduces a novel indicator combining neutrophil count an...

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Bibliographic Details
Main Authors: Jiaqi Lou, Hong Kong, Ziyi Xiang, Xiaoyu Zhu, Shengyong Cui, Jiliang Li, Guoying Jin, Neng Huang, Xin Le, Youfen Fan, Sida Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
intensive care unit
MIMIC-IV database
mortality
sepsis
neutrophil
prognostic nutritional index
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1603104/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1603104/full

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