Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay

QR Code

Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay

Toxoplasma gondii (T. gondii) virulence in mice depends on different multiprotein complexes that assemble at the parasitophorous vacuole membrane (PVM) of the parasite. Individual rhoptry proteins within these complexes inhibit different Immunity-Related GTPases (IRG proteins). The rhoptry pseudokin...

Full description

Saved in:

Bibliographic Details
Main Authors:	Shishir Singh, Mateo Murillo-León, Aura María Bastidas Quintero, Florence Melbert, Klaus Pfeffer, Daniel Degrandi, Tobias Steinfeldt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	host cell resistance co-evolution IRG/GBP proteins T. gondii virulence pseudokinases
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593785/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Identification of GBP6 as a potential prognostic biomarker in esophageal carcinoma by integrated bioinformatics analysis and experiment validation
by: Shilin Fang, et al.
Published: (2025-12-01)

Molecular quantification of gbpA1 gene expression in Vibrio cholerae exposed to Hunteria umbellata methanol leaf extract
by: Titilola F. SALISU, et al.
Published: (2025-06-01)

An Approach To Study The Effects of GBP/USD Exchange Rate and Gold Prices on Brent Oil Prices Using Autoregressive Distributed Lag (ARDL)
by: Shaho Muhammad Wstabdullah, et al.
Published: (2023-01-01)

Interactions between particulate matter and bacteria during cowshed PM2.5-induced respiratory injury initiates GBP2/Caspase-11/NLRP3-mediated intracellular bacterial defense and pyroptosis
by: Xiaohui Du, et al.
Published: (2025-07-01)

[SPA] EL SOCIALISMO CABETIANO: LA HERENCIA UTÓPICA DE MORO EN LA ESPAÑA DEL SIGLO XIX // CABETIAN SOCIALISM: MORE'S UTOPIAN HERITAGE IN NINETEENTH-CENTURY SPAIN
by: Mateo Parisi
Published: (2018-06-01)

Carlos Battilana, Primeras luces
by: Mateo Sturla
Published: (2025-07-01)

Editorial Dossier AREA 25
by: Fernando Murillo
Published: (2019-10-01)

L'avaluació de la formació a l'empresa
by: Joan Mateo Andrés
Published: (1991-01-01)

Claus de la transició a l’Espai Europeu d’Educació Key factors in the transition to the European Higher Education Area Claves de la transición al Espacio Europeo de Educación Superior
by: Joan Mateo Andrés
Published: (2010-01-01)

Controvèrsies metodològiques de la investigació
by: Joan Mateo Andrés
Published: (2001-01-01)

State Support for Activities of Siberian (East Siberian) Department of Imperial Russian Geographical Society in Second Half of 19th Century
by: E. V. Igumnov
Published: (2022-12-01)

Itaconic Acid: A Regulator of Immune Responses and Inflammatory Metabolism
by: Kai Ma, et al.
Published: (2025-07-01)

Planear las periferias metropolitanas de América Latina. ¿Hacia la rurbanización?
by: Fernando Néstor Murillo
Published: (2021-05-01)

¿Sustentabilidad vs. megaproyectos? Lecciones de Qhapaq Ñan y el Tren Maya, dos programas regionales de promoción del patrimonio y la movilidad en América Latina
by: Fernando Néstor Murillo
Published: (2022-01-01)

¿Sustentabilidad vs. megaproyectos? Lecciones de Qhapaq Ñan y el Tren Maya, dos programas regionales de promoción del patrimonio y la movilidad en América Latina
by: Fernando Néstor Murillo
Published: (2022-01-01)

Planear las periferias metropolitanas de América Latina. ¿Hacia la rurbanización?
by: Fernando Néstor Murillo
Published: (2021-06-01)

Sustentabilidad vs. megaproyectos? Lecciones del Qhapaq Ñan y el Tren Maya, dos programas regionales de promoción del patrimonio y la movilidad en América Latina
by: Fernando Néstor Murillo
Published: (2022-01-01)

O grupo das esquizofrenias ou demência precoce: relatório apresentado ao III Congresso Brasileiro de Neurologia, Psiquiátrica e Medicina Legal. Rio de Janeiro. Julho de 1929
by: Murillo de Campos
Published: (2010-12-01)

['¿Sustentabilidad vs. megaproyectos? Lecciones de Qhapaq Ñan y el Tren Maya, dos programas regionales de promoción del patrimonio y la movilidad en América Latina']
by: Fernando Néstor Murillo
Published: (2022-01-01)

Planear las periferias metropolitanas de América Latina. ¿Hacia la rurbanización?
by: Fernando Néstor Murillo
Published: (2021-05-01)

['Planear las periferias metropolitanas de América Latina. ¿Hacia la rurbanización?']
by: Fernando Néstor Murillo
Published: (2021-05-01)

Covid-19 y neoliberalismo
by: Juan Pablo Murillo
Published: (2023-08-01)

Delírio alucinatório crônico em um preto brasileiro, filho de africanos
by: Murillo de Campos
Published: (2010-12-01)

INFLUENCIA DE LAS HABILIDADES SOCIOEMOCIONALES EN EL DESARROLLO ACADÉMICO DE LOS ESTUDIANTES DE BÁSICA SECUNDARIA: UN ANÁLISIS DOCUMENTAL
by: Liliana Murillo Carrillo
Published: (2025-07-01)

Sobre la reformulación y sus marcadores
by: Silvia Murillo Ornat
Published: (2017-12-01)

“No nosso mesmo Brasil mil exemplos encontrei”: as províncias do Brasil e a experiência insurgente (1817-1850)
by: Murillo Dias Winter
Published: (2023-12-01)

BLISK Fabrication by Linear Friction Welding
by: García, Antonio M. Mateo
Published: (2011)

Urban Heat Islands and Land-Use Patterns in Zagreb: A Composite Analysis Using Remote Sensing and Spatial Statistics
by: Dino Bečić, et al.
Published: (2025-07-01)

El camino de Turquía hacia la Unión Europea: Aspectos de la reforma del derecho penal turco como requisito para su incorporación a la UE.
by: Rebeca de Mateo Peña
Published: (2011-06-01)

Durability: Redefining Performance in Endurance Sports
by: Manuel Mateo, et al.
Published: (2025-06-01)

De patricios y nación
by: María Cruz Romeo Mateo
Published: (2005-04-01)

<i>TRIB1</i> and <i>TRPS1</i> Gene Polymorphisms Are Associated with the Incidence of Acute Coronary Syndrome and Plasma Lipid Concentrations
by: Gilberto Vargas-Alarcón, et al.
Published: (2025-05-01)

[es] "DEL PODER Y SUS CRÍTICOS EN EL MUNDO IBÉRICO DEL SIGLO DE ORO"
by: Francisco José Pancorbo Murillo
Published: (2014-06-01)

[spa] "COLOQUIO DE LAS DAMAS"
by: Francisco José Pancorbo Murillo
Published: (2014-12-01)

Exploring Workforce Factors in the Data Fields
by: Angela Murillo, et al.
Published: (2025-07-01)

Intrinsic happiness: The seed inside each person
by: María Gracia Murillo Deglane
Published: (2018-12-01)

El branding interno como antecedente de la autoestima basada en la organización: Un estudio en una cadena de restaurantes
by: Enrique Martín Murillo Othón
Published: (2019-11-01)

Hacia una propuesta de rúbrica para la evaluación de la calidad de comentarios de código en Java
by: Juan Carlos García Murillo
Published: (2023-06-01)

Spanish Version of the Measure of Processes of Care (20 Items): Psychometric Properties
by: Manuel Pacheco-Molero, et al.
Published: (2025-07-01)

Simple Closed-Form Solution to Predict Short-Range Surface Plasmons in Thin Films Bounded by Asymmetric Media and Its Application to Hole Arrays
by: M. Lorente-Crespo, et al.
Published: (2016-01-01)