Oral Health and Cognitive Decline: A Systematic Review of the Periodontitis–Alzheimer’s Connection

Oral Health and Cognitive Decline: A Systematic Review of the Periodontitis–Alzheimer’s Connection

Background: Alzheimer’s disease (AD), a neurodegenerative disorder characterized by cognitive decline, has been linked to systemic inflammation. Periodontal disease (PD), a chronic inflammatory condition, may contribute to neurodegeneration via microbial dysbiosis and inflammatory pathways. This sys...

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Bibliographic Details
Main Authors: Angelo Michele Inchingolo, Alessio Danilo Inchingolo, Fabio Piras, Pasquale Avantario, Laura Ferrante, Gregorio Paduanelli, Francesco Inchingolo, Andrea Palermo, Gianna Dipalma, Massimo Corsalini
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Applied Sciences
Subjects:
Alzheimer’s disease
periodontal disease
neuroinflammation
microbial dysbiosis
systemic inflammation
cognitive decline
Online Access:https://www.mdpi.com/2076-3417/15/12/6728
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