Whipple’s endocarditis diagnosed non-invasively with plasma microbial cell-free DNA sequencing

Whipple’s endocarditis diagnosed non-invasively with plasma microbial cell-free DNA sequencing

Tropheryma whipplei bioprosthetic aortic valve endocarditis was diagnosed in a 55-year-old patient who presented with neurologic signs. Next-generation sequencing (NGS) of microbial cell-free DNA (cfDNA) detected a profound level of the organism in a plasma sample. This entity often comes to diagnos...

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Bibliographic Details
Main Authors: Najy Issa, Zaid Naseer, Andrew Mangano, Norman Bernstein
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
Subjects:
Whipple's Endocarditis
Microbial Cell-Free DNA
NGS
Tropheryma Whipplei
Culture-negative Endocarditits
Bioprosthetic Aortic Valve
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925001647
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http://www.sciencedirect.com/science/article/pii/S2214250925001647

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