A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns.
The locus coeruleus (LC) norepinephrine (NE) system is involved in a variety of physiological and pathophysiological processes. Refining our understanding of LC function largely relies on selective transgene expression in LC-NE neurons, allowing targeted manipulation and readout of noradrenergic neu...
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| Main Authors: | Chantal Wissing, Lena S Eschholz, Maxime Maheu, Kathrin Sauter, Fabio Morellini, J Simon Wiegert, Alexander Dieter |
|---|---|
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Public Library of Science (PLoS)
2025-07-01
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| 叢編: | PLoS Biology |
| 在線閱讀: | https://doi.org/10.1371/journal.pbio.3003228 |
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