Therapeutic Potential of Rho Kinase Inhibitors in Corneal Disease: A Systematic Review of Preclinical and Clinical Studies

Therapeutic Potential of Rho Kinase Inhibitors in Corneal Disease: A Systematic Review of Preclinical and Clinical Studies

<b>Background/Objectives:</b> Rho-associated coiled-coil-containing protein kinase inhibitors (ROCKis) have now become known as modulators of corneal endothelial wound repair and cell survival. However, evidence remains fragmented across laboratory and clinical reports. We performed a sy...

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Bibliographic Details
Main Authors: Laura Andreea Ghenciu, Diana Andrei, Claudia Borza, Roxana Iacob, Emil Robert Stoicescu, Sorin Lucian Bolintineanu, Daniela Iacob, Ovidiu Alin Haţegan
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
Rho kinase inhibitors
Fuchs dystrophy
limbal stem cells deficiency
bullous keratopathy
ripasudil
netarsudil
Online Access:https://www.mdpi.com/2227-9059/13/7/1602
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