A high effective expression of human D-glucuronyl C5-epimerase with dimer structure in Escherichia coli
IntroductionHeparan sulfate (HS), a linear anionic polysaccharide, participates in many physiological processes and exhibits many pharmacological activities. D-glucuronyl C5-epimerase (Glce) is one of the key enzymes in the biosynthesis of heparan sulfate proteoglycans. However, the recombinant Glce...
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Main Authors: | Qin-xia Song, Li-jian Guo |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Microbiology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1641598/full |
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