On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

The zinc finger 469 gene (ZNF469) is a single‐exon gene predicted to encode a protein of 3953 amino acids. Despite pathogenic ZNF469 variants being associated with Brittle Cornea Syndrome (BCS), relatively little is known about ZNF469 beyond its participation in regulating the expression of genes en...

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Bibliographic Details
Main Authors: Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:FEBS Open Bio
Subjects:
biomolecular condensates
intrinsically disordered regions
midbody
nuclear speckles
proteasomes
stress granules
Online Access:https://doi.org/10.1002/2211-5463.70034
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https://doi.org/10.1002/2211-5463.70034

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