Comparison of the Expression of Acetylated Histones H3 and H4 and the Deacetylase Enzymes HDACs 1, 2, and 6 in Neoplastic and Nonneoplastic Canine Mammary Tissues

Comparison of the Expression of Acetylated Histones H3 and H4 and the Deacetylase Enzymes HDACs 1, 2, and 6 in Neoplastic and Nonneoplastic Canine Mammary Tissues

Epigenetic alterations play a crucial role in the pathogenesis of cancer, as changes in the expression of DNA-associated proteins can affect gene expression. However, these changes may be reversible following treatment. This study aimed to evaluate the expression of acetylated histones H3 and H4 and...

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Main Authors: Igor Luiz Salardani Senhorello, Oscar Rodrigo Sierra Matiz, Isabela Cristina Canavari, Giovanni Vargas-Hernandez, Letícia Abrahão Anai, Roberto Andrés Navarrete Ampuero, Josiane Moraes Pazzini, Cibele Maria Prado, Flávio Vieira Meirelles, Rosemeri de Oliveira Vasconcelos, Mirela Tinucci-Costa
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/vmi/3876142
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http://dx.doi.org/10.1155/vmi/3876142

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