Functional Expression of NMDA Receptors in SH-SY5Y Neuroblastoma Cells Following Long-Term RA/BDNF-Induced Differentiation

Functional Expression of NMDA Receptors in SH-SY5Y Neuroblastoma Cells Following Long-Term RA/BDNF-Induced Differentiation

SH-SY5Y neuroblastoma cells can be effectively differentiated into a neuronal phenotype using retinoic acid (RA) and brain-derived neurotrophic factor (BDNF), making them a valuable in vitro model for studying neuronal differentiation. This study aimed to investigate the electrophysiological propert...

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Bibliographic Details
Main Authors: Ya-Jean Wang, Yun-Hsiang Chen, Eric Hwang, Che-Jui Yeh, You-Xuan Liu, Hwei-Hsien Chen, Sheng-Nan Wu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:NeuroSci
Subjects:
SH-SY5Y cells
differentiation
evoked action potential
NMDA receptor-mediated current
atorvastatin
Online Access:https://www.mdpi.com/2673-4087/6/2/47
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