Investigating SMYD3 role during oocyte maturation in a 3D follicle-enclosed oocyte in vitro model in sheep

Investigating SMYD3 role during oocyte maturation in a 3D follicle-enclosed oocyte in vitro model in sheep

BackgroundSMYD3 is a histone methyltransferase known for its dual role in modifying both histone and non-histone proteins. Despite its established involvement in somatic cell function and oncogenesis, its role in mammalian oogenesis and early embryonic development remains unclear. This study aimed t...

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Main Authors: Chiara Camerano Spelta Rapini, Alessia Peserico, Chiara Di Berardino, Giulia Capacchietti, Camila Rojo-Fleming, Andrada-Ioana Damian-Buda, Irem Unalan, Aldo Roberto Boccaccini, Valentina Grossi, Mauro Mattioli, Barbara Barboni
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SMYD3
follicle-enclosed oocyte in vitro maturation (FEO-IVM)
ovine oocyte competence
cumulus-oocyte metabolic coupling
hCG-dependent signaling pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1625914/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1625914/full

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