Site‐Specific Mutations on KRAS, NRAS, and BRAF Corelate With the Frequency of ctDNA in Colorectal Cancer

Site‐Specific Mutations on KRAS, NRAS, and BRAF Corelate With the Frequency of ctDNA in Colorectal Cancer

ABSTRACT Background Early prediction of metastatic risk after tumor resection for colorectal cancer (CRC) is critical to improve treatment outcomes. Although circulating tumor DNA (ctDNA) is an important biomarker in CRC patients, positivity is variable because cutoff values for each gene have not b...

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Main Authors: Fumihiro Yoshimura, Yoichiro Yoshida, Teppei Yamada, Keita Tanaka, Takaomi Hayashi, Hideki Shimaoka, Ryohei Sakamoto, Naoya Aisu, Gumpei Yoshimatsu, Suguru Hasegawa
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Reports
Subjects:
BRAF
circulating tumor DNA
colorectal cancer
KRAS
liquid biopsy
NRAS
Online Access:https://doi.org/10.1002/cnr2.70292
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https://doi.org/10.1002/cnr2.70292

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