Resistance of breast cancer cells to all-trans retinoic acid is associated with a decrease in the basal level of nuclear receptor <i>RARα</i> expression and induction of cytochrome <i>CYP26A1</i> and <i>CYP26B1</i> expression

Introduction. Retinoic acid (RA) is a key regulator of cell differentiation and a critical player in such systemic processes in the body as embryonic development, immune system cell maturation and functioning, tissue remodeling and several others. This compound displays an antitumor activity due to...

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Bibliographic Details
Main Authors: A. D. Enikeev, A. V. Komelkov, N. V. Elkina, M. E. Akselrod, S. A. Kuzmichev, E. M. Tchevkina
Format: Article
Language:Russian
Published: ABV-press 2022-06-01
Series:Успехи молекулярной онкологии
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Online Access:https://umo.abvpress.ru/jour/article/view/440
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