Fos expression in the periaqueductal gray, but not the ventromedial hypothalamus, is correlated with psychosocial stress-induced cocaine-seeking behavior in rats

Fos expression in the periaqueductal gray, but not the ventromedial hypothalamus, is correlated with psychosocial stress-induced cocaine-seeking behavior in rats

Psychosocial stressors are known to promote cocaine craving and relapse in humans but are infrequently employed in preclinical relapse models. Consequently, the underlying neural circuitry by which these stressors drive cocaine seeking has not been thoroughly explored. Using Fos expression analyses,...

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Bibliographic Details
Main Authors: Nicole M. Hinds, Ireneusz D. Wojtas, Desta M. Pulley, Stephany J. McDonald, Colton D. Spencer, Milena Sudarikov, Nicole E. Hubbard, Colin M. Kulick-Soper, Samantha de Guzman, Sara Hayden, Jessica J. Debski, Bianca Patel, Douglas P. Fox, Daniel F. Manvich
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Addiction Neuroscience
Subjects:
Cocaine
Reinstatement
Social defeat stress
Footshock
Periaqueductal gray
Ventromedial hypothalamus
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392525000239
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http://www.sciencedirect.com/science/article/pii/S2772392525000239

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