Trialing addiction neurocircuitry targets and directionality of brain stimulation effects: A deep TMS/fMRI trial in people with alcohol use disorder

Trialing addiction neurocircuitry targets and directionality of brain stimulation effects: A deep TMS/fMRI trial in people with alcohol use disorder

Background: Excessive alcohol consumption is a global health concern, with an estimated 400 million people living with alcohol use disorder (AUD). Current treatments for AUD have limited efficacy and fail to address its diverse neurobiological underpinnings. There are at least two cortico-striatal c...

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Bibliographic Details
Main Authors: Daniel J. Fehring, Jordan Morrison-Ham, Annalee L. Cobden, Justin Mahlberg, Mengxia Gao, Claire E. Kelly, Arshiya Sangchooli, Devon Stoliker, Emily Giddens, Brody Quinn, Antonia Cholewick, Luiza Bonfim Pacheco, Adeel Razi, Natalia Albein-Urios, Antonio Verdejo-Garcia
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Contemporary Clinical Trials Communications
Subjects:
Deep transcranial magnetic stimulation (dTMS)
Alcohol use disorder (AUD)
Transcranial magnetic stimulation (TMS)
Functional magnetic Resonance imaging (fMRI)
Spectral dynamic causal modeling (spDCM)
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865425000894
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