FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA
Preeclampsia (PE) and fetal growth restriction (FGR) are major contributors to maternal and perinatal morbidity and mortality worldwide. In Bulgaria, the burden of these conditions is compounded by delayed diagnosis and limited access to comprehensive early screening. First-trimester screening enabl...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Peytchinski Publishing
2025-07-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | https://www.journal-imab-bg.org/issues-2025/issue3/2025vol31-issue3_6352-6360.pdf |
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| Summary: | Preeclampsia (PE) and fetal growth restriction (FGR) are major contributors to maternal and perinatal morbidity and mortality worldwide. In Bulgaria, the burden of these conditions is compounded by delayed diagnosis and limited access to comprehensive early screening. First-trimester screening enables the identification of high-risk pregnancies through maternal risk factors, biomarkers, and Doppler ultrasonography. Preventive strategies, particularly the timely administration of low-dose aspirin, have proven effective in reducing the incidence of early-onset PE and FGR. This review summarizes current evidence on the pathophysiology, screening models, and prevention strategies for PE and FGR, with emphasis on their implementation in Bulgarian clinical practice. Recommendations are provided for enhancing maternal care through national policies and expanded screening programs. |
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| ISSN: | 1312-773X |