TREATMENT OF <em>BRAF</em><sup>V600E</sup> POSITIVE ANAPLASTIC THYROID CARCINOMA: CASE REPORT

TREATMENT OF <em>BRAF</em><sup>V600E</sup> POSITIVE ANAPLASTIC THYROID CARCINOMA: CASE REPORT

Anaplastic thyroid cancer is one of the most aggressive and fatal human carcinomas. A significant experience in using various kinase inhibitors for anaplastic thyroid cancer therapy has been accumulated worldwide. The most encouraging results were obtained after using a combination of b-Raf and MEK...

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Main Authors: P. A. Nikiforovich, P. O. Rumiantsev, I. V. Sleptsov, T. V. Ustinova, K. Yu. Slashchuk, S. L. Vorobyev, S. S. Serzhenko, A. Yu. Abrosimov, A. V. Kudryavtseva, A. A. Semenov, R. A. Chernikov, A. A. Polyakov, A. A. Fedenko, L. V. Bolotina, A. A. Paychadze, A. Y. Trushin, A. D. Kaprin, G. S. Zakharova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2020-10-01
Series:Сибирский онкологический журнал
Subjects:
anaplastic thyroid cancer
brafv600e mutation
targeted therapy
neoadjuvant therapy
Online Access:https://www.siboncoj.ru/jour/article/view/1588
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