Chronic reduction of synaptic proteins in the epileptogenic lesion of patients with hippocampal sclerosis

Disturbance of synaptic proteins in the epileptogenic lesion is considered the basis for drug-resistant focal epilepsy. However, details of these molecular changes remain unknown because brain tissues are typically uncollectable from live patients. Using surgically excised brain tissues from epilept...

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Bibliographic Details
Main Authors: Akiko Oota-Ishigaki, Nami Suzuki, Keiya Iijima, Yutaro Takayama, Yuiko Kimura, Kotaro Hattori, Masaki Iwasaki, Takashi Hayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1635852/full
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