TLR9 gene polymorphism -1237T/C (rs5743836) is associated with low IgG antibody response against PvCSP variants in symptomatic P. vivax infections in Venezuela.

<h4>Background</h4>Clinical immunity to malaria has been associated with humoral immune responses targeting asexual-stage parasite proteins. However, the variability in antibody-driven responses may be influenced by genetic factors in the human host. This study aimed to evaluate the freq...

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Bibliographic Details
Main Authors: Fhabián S Carrión-Nessi, Eva Salazar-Alcalá, David A Forero-Peña, Kellys A Curiel, Mary Lopez-Perez, Mercedes Fernández-Mestre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013262
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