MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD
Summary: Rhabdomyosarcoma (RMS) is the most common soft tissue cancer among children, characterized by a skeletal muscle lineage that is impaired from undergoing terminal differentiation. NF-κB is constitutively active in cancer cells and plays a critical role in cell survival. Although NF-κB is als...
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Main Authors: | Alexander R. Oles, Peter Y. Yu, Abasi-ama Udeme, Sudarshana Sharma, Priya Londhe, Benjamin R. Pryce, Erin E. Talbert, Eric M. Hill, Carlos J. Miranda, Brian K. Kaspar, Michael A. Arnold, Jack Hyland, Cheryl A. London, Peter J. Houghton, David J. Wang, Ryan D. Roberts, Denis C. Guttridge |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-08-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225014105 |
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