MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD

MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD

Summary: Rhabdomyosarcoma (RMS) is the most common soft tissue cancer among children, characterized by a skeletal muscle lineage that is impaired from undergoing terminal differentiation. NF-κB is constitutively active in cancer cells and plays a critical role in cell survival. Although NF-κB is als...

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Autori principali: Alexander R. Oles, Peter Y. Yu, Abasi-ama Udeme, Sudarshana Sharma, Priya Londhe, Benjamin R. Pryce, Erin E. Talbert, Eric M. Hill, Carlos J. Miranda, Brian K. Kaspar, Michael A. Arnold, Jack Hyland, Cheryl A. London, Peter J. Houghton, David J. Wang, Ryan D. Roberts, Denis C. Guttridge
Natura: Articolo
Lingua:inglese
Pubblicazione: Elsevier 2025-08-01
Serie:iScience
Soggetti:
Cell biology
Cancer
Accesso online:http://www.sciencedirect.com/science/article/pii/S2589004225014105
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http://www.sciencedirect.com/science/article/pii/S2589004225014105

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