Enhanced transdermal delivery of lidocaine cream via ultrasound and microneedle rollers

ObjectiveThe aim of this study is to determine the most effective physical parameters for optimizing the transdermal delivery of lidocaine cream.MethodsPreliminary experiments were conducted to optimize ultrasound settings while ensuring safety, guided by visual and histopathological evaluations fol...

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Bibliographic Details
Main Authors: Jiaxiao Sun, Yang Yang, Juanjuan Zheng, Hao Liang, Feng Yan, Wensheng Zhang, Wenqin Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1612145/full
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