Interaction Between CYP1A2-Related Caffeine Metabolism and Vitamin B12/Folate Status in Patients with Metabolic Syndrome: A Novel Biomarker Axis

Interaction Between CYP1A2-Related Caffeine Metabolism and Vitamin B12/Folate Status in Patients with Metabolic Syndrome: A Novel Biomarker Axis

<b>Background/Objectives</b>: The prevalence of metabolic syndrome (MetS) is steadily increasing worldwide, driven by complex genetic, nutritional, and environmental factors. Caffeine metabolism, primarily mediated by CYP1A2 (though other enzymes such as CYP1A1 may also be involved), and...

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Bibliographic Details
Main Authors: Laura Claudia Popa, Ahmed Abu-Awwad, Simona Sorina Farcas, Simona-Alina Abu-Awwad, Nicoleta Ioana Andreescu
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Metabolites
Subjects:
metabolic syndrome
caffeine metabolism
cytochrome P-450 CYP1A2
vitamin B12
folic acid
personalized medicine
Online Access:https://www.mdpi.com/2218-1989/15/7/450
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