Age-related inflammatory biomarkers in early-onset osteoporosis in females with Gaucher disease

Gaucher disease (GD), the most common lysosomal disorder, is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Accumulation of the substrate, glycosylceramide (Gb-1), and its lysosomal derivative, glucosylsphingosine, Lyso-Gb1, are associated with immune-mediated inflammation. Patient...

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Auteurs principaux: Margarita M. Ivanova, Julia Dao, Neil Kasaci, Fang Huang, Emily Nguyen, Ozlem Goker-Alpan
Format: Article
Langue:anglais
Publié: Frontiers Media S.A. 2025-07-01
Collection:Frontiers in Endocrinology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fendo.2025.1606218/full
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