The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study
Context: Electronic cigarette smoking (ECS) is a rising concern among young people. Aims: This study aimed to compare perception, clinical findings, and cytomorphological changes in buccal mucosa of electronic cigarette smokers and nonsmokers. Settings and Design: A cross-sectional study includes 10...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1352_24 |
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| author | Sura A. A. Fuoad Al Bayati Shatha S. Al Sharbatti Eman H. Ibrahim Sunil K. Bylappa Dania K. H. Saleh |
| author_facet | Sura A. A. Fuoad Al Bayati Shatha S. Al Sharbatti Eman H. Ibrahim Sunil K. Bylappa Dania K. H. Saleh |
| author_sort | Sura A. A. Fuoad Al Bayati |
| collection | DOAJ |
| description | Context:
Electronic cigarette smoking (ECS) is a rising concern among young people.
Aims:
This study aimed to compare perception, clinical findings, and cytomorphological changes in buccal mucosa of electronic cigarette smokers and nonsmokers.
Settings and Design:
A cross-sectional study includes 100 consented university students aged ≥18 years, of both genders.
Methods and Material:
Tobacco, and alcohol users, those with systemic diseases were excluded. A validated questionnaire was administered, clinical examination, cytomorphological analysis were performed.
Statistical Analysis Used:
The obtained data were analyzed using SPSS version 28 software. The chi-square test and Fisher’s exact test, student’s t test was used.
Results:
A significant change observed in the ECS tongue/buccal mucosa, specifically, white discoloration (20% vs. 6%, P = 0.037). Dry mouth and a feeling stickiness in the mouth were more common among ECS (62% vs. 30%, P = 0.001), and (48% vs. 20%, P = 0.003) respectively. Significant cytological changes found in ECS with P < 0.001 for nuclear size (increase in 48% vs. 0%), nuclear-cytoplasmic ratio (increased in 46% vs. 0%), binucleation (presence 66% vs. 8%), a moderate perinuclear halo (18% vs. 0%), cytoplasmic granules (moderate/severely present in 62% vs. 2%), and moderate/severe inflammation (present in 18% vs. 8%). The average nuclear size (μ) was significantly greater in ECS than in nonsmokers (10.434 vs. 8.480) and presence of micronuclei (20% vs. 4%, P = 0.014).
Conclusion:
There is a significant association between ECS and dry mouth signs and symptoms, white discoloration of buccal mucosa, and oral cytomorphological changes suggesting potential malignant transformation. |
| format | Article |
| id | doaj-art-e60dfa1d1ebe48c5a8a9bbd5e9d40cd4 |
| institution | Matheson Library |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-e60dfa1d1ebe48c5a8a9bbd5e9d40cd42025-07-05T11:19:54ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-06-0117Suppl 2S1131S113710.4103/jpbs.jpbs_1352_24The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional StudySura A. A. Fuoad Al BayatiShatha S. Al SharbattiEman H. IbrahimSunil K. BylappaDania K. H. SalehContext: Electronic cigarette smoking (ECS) is a rising concern among young people. Aims: This study aimed to compare perception, clinical findings, and cytomorphological changes in buccal mucosa of electronic cigarette smokers and nonsmokers. Settings and Design: A cross-sectional study includes 100 consented university students aged ≥18 years, of both genders. Methods and Material: Tobacco, and alcohol users, those with systemic diseases were excluded. A validated questionnaire was administered, clinical examination, cytomorphological analysis were performed. Statistical Analysis Used: The obtained data were analyzed using SPSS version 28 software. The chi-square test and Fisher’s exact test, student’s t test was used. Results: A significant change observed in the ECS tongue/buccal mucosa, specifically, white discoloration (20% vs. 6%, P = 0.037). Dry mouth and a feeling stickiness in the mouth were more common among ECS (62% vs. 30%, P = 0.001), and (48% vs. 20%, P = 0.003) respectively. Significant cytological changes found in ECS with P < 0.001 for nuclear size (increase in 48% vs. 0%), nuclear-cytoplasmic ratio (increased in 46% vs. 0%), binucleation (presence 66% vs. 8%), a moderate perinuclear halo (18% vs. 0%), cytoplasmic granules (moderate/severely present in 62% vs. 2%), and moderate/severe inflammation (present in 18% vs. 8%). The average nuclear size (μ) was significantly greater in ECS than in nonsmokers (10.434 vs. 8.480) and presence of micronuclei (20% vs. 4%, P = 0.014). Conclusion: There is a significant association between ECS and dry mouth signs and symptoms, white discoloration of buccal mucosa, and oral cytomorphological changes suggesting potential malignant transformation.https://journals.lww.com/10.4103/jpbs.jpbs_1352_24clinical findingscytomorphological changeselectronic cigarette smokersself-reported perception |
| spellingShingle | Sura A. A. Fuoad Al Bayati Shatha S. Al Sharbatti Eman H. Ibrahim Sunil K. Bylappa Dania K. H. Saleh The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study Journal of Pharmacy and Bioallied Sciences clinical findings cytomorphological changes electronic cigarette smokers self-reported perception |
| title | The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study |
| title_full | The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study |
| title_fullStr | The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study |
| title_full_unstemmed | The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study |
| title_short | The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study |
| title_sort | impact of electronic cigarettes on oral health analytic cross sectional study |
| topic | clinical findings cytomorphological changes electronic cigarette smokers self-reported perception |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1352_24 |
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