Polygonatum polysaccharides as gut microbiota modulators: implications for autophagy-dependent PD-L1 clearance in cancer immunotherapy

The purpose of this review article is to examine the biotransformation of Polygonatum polysaccharides and the role that gut microbiota plays in that biotransformation. In the past years, PD-L1 has come under much attention as an immune checkpoint target and autophagy-lysosomal mediated degradation o...

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Bibliographic Details
Main Authors: Yongjie Li, Feng Jiang, Ting Wang, Min Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1612644/full
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