Carbonyl group-assisted 1,3-amine addition to α,β-unsaturated aldehydes

An unusual 1,3-addition products were obtained when amines were reacted with α,β-unsaturated aldehydes compounds in the presence of iodine and an oxidant. The versatile unsaturated α-amino acetals are highly useful amino acid derivatives and can be converted to a wide variety of synthetically useful...

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Bibliographic Details
Main Authors: Zhenguo Zhang, Mi Ren, Ming-Zhu Lu, Zhenhua Jia, Teck-Peng Loh
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-05-01
Series:Green Synthesis and Catalysis
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666554924000462
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