Critical role of cytochrome c1 and its cleavage in porcine reproductive and respiratory syndrome virus nonstructural protein 4-induced cell apoptosis via interaction with nsp4

Critical role of cytochrome c1 and its cleavage in porcine reproductive and respiratory syndrome virus nonstructural protein 4-induced cell apoptosis via interaction with nsp4

Porcine reproductive and respiratory syndrome virus (PRRSV) actively induces cell apoptosis both in vitro and in vivo, which can contribute critically to viral pathogenesis. Previous studies have shown that the PRRSV nonstructural protein 4 (nsp4) is an important mediator of this process, but the un...

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Bibliographic Details
Main Authors: Feng ZHANG, Peng GAO, Xin-na GE, Lei ZHOU, Xin GUO, Han-chun YANG
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-11-01
Series:Journal of Integrative Agriculture
Subjects:
PRRSV
nonstructural protein4 (nsp4)
cytochrome c1 (cyto.c1)
interaction
cleavage
apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311917616708
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