Activation of the Rat P2X7 Receptor by Functionally Different ATP Activation Sites

The homotrimeric P2X7 receptor (P2X7R) contains three ATP<sup>4−</sup> binding sites in its ectodomain. Here, we investigated the role of individual ATP<sup>4−</sup> activation sites in rat P2X7R (rP2X7R) using trimeric concatemers consisting of either three wild-type subunit...

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Bibliographic Details
Main Authors: Fritz Markwardt, Malte Berthold, Sanaria Hawro Yakoob, Günther Schmalzing
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/12/855
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