Urotensin II system contributes to ischemic acute kidney injury in neonatal pigs
The urotensin II (UII) system comprises UII, UII-related peptide (URP), and their shared receptor UT. Bioactive UII can be generated from its precursor, prepro-UII, through proteolytic cleavage by the serine protease furin. The kidney serves as a significant source of UII, with elevated levels repor...
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Main Authors: | Julia E. de la Cruz, Olugbenga S. Michael, Praghalathan Kanthakumar, Olufunke O. Falayi, Samson A. Iwhiwhu, Jeremiah M. Afolabi, Ravi Kumar, Hitesh Soni, Adebowale Adebiyi |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
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Series: | Renal Failure |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2534018 |
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