Urotensin II system contributes to ischemic acute kidney injury in neonatal pigs

Urotensin II system contributes to ischemic acute kidney injury in neonatal pigs

The urotensin II (UII) system comprises UII, UII-related peptide (URP), and their shared receptor UT. Bioactive UII can be generated from its precursor, prepro-UII, through proteolytic cleavage by the serine protease furin. The kidney serves as a significant source of UII, with elevated levels repor...

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Bibliographic Details
Main Authors: Julia E. de la Cruz, Olugbenga S. Michael, Praghalathan Kanthakumar, Olufunke O. Falayi, Samson A. Iwhiwhu, Jeremiah M. Afolabi, Ravi Kumar, Hitesh Soni, Adebowale Adebiyi
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Urotensin II system
furin
renal ischemia-reperfusion
acute kidney injury
neonatal pigs
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2534018
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2534018

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