Ferroptosis: A critical link to treatment resistance in esophageal carcinoma

Summary: Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxide accumulation, induces lethal oxidative damage and disrupts cell membrane integrity. Its role in malignant tumors, such as esophageal carcinoma (EC), is increasingly recognized, offering a promising therapeu...

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Bibliographic Details
Main Authors: Ming-Xin Tang, Jin-Feng Chen, Fa-Zhi Zhao, Jun Peng
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011629
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