Sestrin2 Overexpression Inhibits Proliferation and Epithelial–Mesenchymal Transition and Induces Autophagy Through the AMPK/mTOR Signaling Pathway in Human Prostate Cancer Cells

Conclusion: Our study suggests that SESN2 inhibits prostate cancer cells by inducing autophagy through the AMPK/mTOR signaling pathway. These results indicate that SESN2 might be a novel target for prostate cancer.

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Bibliographic Details
Main Authors: Yae-Ji Kim, Hui-Ju Lee, Kyung-Hyun Kim, Geum-Lan Hong, Ju-Young Jung
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/proc/8842203
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