<i>Alpinia zerumbet</i> Extract Mitigates PCB 126-Induced Neurotoxicity and Locomotor Impairment in Adult Male Mice

<i>Alpinia zerumbet</i> Extract Mitigates PCB 126-Induced Neurotoxicity and Locomotor Impairment in Adult Male Mice

Polychlorinated biphenyls (PCBs) are synthetic chemical compounds that have bioaccumulated and contaminated the entire global ecosystem, causing neurotoxic effects. However, polyphenols may have protective effects against this neurotoxicity. We aimed to investigate the neuroprotective effect of a hy...

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Main Authors: Paula Hosana Fernandes da Silva, Jemima Isnardo Fernandes, Matheus Pontes de Menezes, Fabrícia Lima Fontes-Dantas, André Luiz Nunes Freitas, Rayane Efraim Correa, Ulisses Cesar de Araujo, Dayane Teixeira Ognibene, Cristiane Aguiar da Costa, Cláudio Carneiro Filgueiras, Alex Christian Manhães, Júlio Beltrame Daleprane, Angela de Castro Resende, Graziele Freitas de Bem
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Scientia Pharmaceutica
Subjects:
<i>Alpinia zerumbet</i>
polychlorinated biphenyls
locomotor deficits
neurotoxicity
neurodegeneration
dopamine metabolism
Online Access:https://www.mdpi.com/2218-0532/93/2/23
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