Phenotype to genotype: A new and rapid approach using whole-genome sequencing.

Phenotype to genotype: A new and rapid approach using whole-genome sequencing.

Forward genetic screening is a powerful approach to assign functions to genes and can be used to elucidate the many genes whose functions remain unknown. A key step in forward genetic screening is mapping: identification of the gene causing the phenotype. Existing mapping methods use a bioinformatic...

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Main Authors: McKenna Feltes, Aleksey V Zimin, Sofia Angel, Nainika Pansari, Monica R Hensley, Jennifer L Anderson, Meng-Chieh Shen, Mackenzie Klemek, Yi Shen, Vighnesh S Ginde, Hannah Kozan, Nhan V Le, Vivian P Truong, Meredith H Wilson, Steven L Salzberg, Steven A Farber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011702
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https://doi.org/10.1371/journal.pgen.1011702

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