Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease [version 1; peer review: 2 approved, 2 approved with reservations]

The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. Although animal models are essential for understanding pancreatic development and disease, they are limited by their low throughput and major species-spec...

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Bibliographic Details
Main Authors: Francesca Maria Spagnoli, Abigail Isaacson, Jean-Francois Darrigrand
Format: Article
Language:English
Published: F1000 Research Ltd 2025-06-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/14-575/v1
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