EDTA enhances cementum-like tissue formation, TGF-β1 & VEGF in rat molars during regenerative endodontics

EDTA enhances cementum-like tissue formation, TGF-β1 & VEGF in rat molars during regenerative endodontics

Abstract This study investigated the influence of ethylenediaminetetraacetic acid (EDTA) irrigation on cementum-like tissue formation and TGF-β1, FGF-2, and VEGF immunolabeling during regenerative endodontic procedures (REPs) in immature rat molars. The lower first molars of 12 four-week-old male ra...

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Main Authors: Alexandre Henrique dos REIS-PRADO, Isabela Joane Prado SILVA, Juliana GOTO, Nathália Evelyn da Silva MACHADO, Gleide Fernandes de AVELAR, Juliano Douglas Silva ALBERGARIA, Raphael Escorsim SZAWKA, Marco Cícero BOTTINO, Luciano Tavares Angelo CINTRA, Edilson ERVOLINO, Antônio Paulino RIBEIRO-SOBRINHO, Francine BENETTI
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2025-06-01
Series:Brazilian Oral Research
Subjects:
Edetic Acid
Fibroblast Growth Factor 2
Regenerative Endodontics
Transforming Growth Factor beta
Vascular Endothelial Growth Factor A
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000100556&lng=en&tlng=en
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