Determination of the Anti-Escherichial Activity of the Pyrimidine Derivative 3-[2-[(4,6-dimethylpyrimidin-2- yl)amino]-2-oxoethyl]quinazolin-4(3H)-one

QR Code

Determination of the Anti-Escherichial Activity of the Pyrimidine Derivative 3-[2-[(4,6-dimethylpyrimidin-2- yl)amino]-2-oxoethyl]quinazolin-4(3H)-one

The aim of this study was to investigate the antimicrobial activity of the pyrimidine derivative 3-[2-[(4,6-dimethylpyrimidin-2-yl)amino]-2-oxoethyl]quinazolin-4(3H)-one against Escherichia coli. The study of antimicrobial activity was carried out in vitro by serial dilutions of the pyrimidine compo...

Full description

Saved in:

Bibliographic Details
Main Authors:	A. A. Tsibizova, A. L. Yasenyavskaya, I. N. Tyurenkov, А. А. Ozerov, M. А. Samotrueva
Format:	Article
Language:	Russian
Published:	LLC "Publishing House OKI" 2023-12-01
Series:	Антибиотики и Химиотерапия
Subjects:	escherichia coli generalized escherichial infection bactericidal activity antimicrobial activity
Online Access:	https://www.antibiotics-chemotherapy.ru/jour/article/view/1057
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Evaluation of the antimicrobial activity of pyrimidine compound 3-(2-benzyloxy-2-oxoethyl)quinazoline-4(3H)-oh in relation to Klebsiella pneumoniae
by: A. B. S. Hmidet, et al.
Published: (2023-04-01)

Screening studies of antimicrobial activity of pyrimidine derivative
by: A. A. Tsibizova, et al.
Published: (2021-12-01)

Study of the Anti-klebsiella Activity of Quinazoline Compounds Containing a Piperazine Ring
by: A. A. Tsibizova, et al.
Published: (2024-11-01)

ANTIMICROBIAL ACTIVITY STUDY OF NEW QUINAZOLIN-4(3H)-ONES AGAINST STAPHYLOCOCCUS AUREUS AND STREPTOCOCCUS PNEUMONIAE
by: M. A. Samotrueva, et al.
Published: (2021-09-01)

Evaluation of Antimicrobial Activity of a Pyrimidine Derivative Against <i>Staphylococcus Aureus</i>
by: A. A. TSIBIZOVA, et al.
Published: (2022-09-01)

STUDY OF THE STABILITY OF THE SUBSTANCE 3-[2-(4-PHENYL-1-PIPERAZINO)-2-OXOETHYL]QUINAZOLINE-4(3Н)-ONE UNDER STRESSFUL CONDITIONS
by: T. A. Gendugov, et al.
Published: (2021-01-01)

Screening Studies of the Antimicrobial Activity of the Pyrimidine Compound 2,2-[6-Bromo-2,4-Dioxoquinazoline-1,3(2H)diyl]bis(N-Carbamimidoylacetamide)
by: A. A. Tsibizova, et al.
Published: (2024-04-01)

Assessment of Acute Toxicity of Quinazoline Derivative 3-[2-oxo-2-(4-Phenylpiperazine-1-yl)Ethyl]quinazoline-4(3h)-oh Active against Opportunistic Microorganisms
by: N. M. Gabitova, et al.
Published: (2023-07-01)

Results of Preclinical Studies of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4-th Bromide in Relation to the Hemostasis System <i>in vivo</i>
by: Y. Wang, et al.
Published: (2024-03-01)

4-phenyl-5-((pyrimidin-2-ylthio)methyl)-1,2,4-triazole-3-thiol as a platform for the synthesis of unsymmetrical disulfides
by: Yu. V. Karpenko, et al.
Published: (2025-03-01)

Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative
by: A. A. Tsibizova, et al.
Published: (2023-09-01)

In silico study of biological activity of 2-[5-(furan-2-yl)-4-phenyl-4n-1,2,4-triazol-3-ylthio]-1-(4-chlorophenylethanone)
by: N. M. Borysenko, et al.
Published: (2025-06-01)

Effect of a pyrimidine derivative on the level of cytokines in conditions of streptococcal wound infection
by: A. A. Tsibizova, et al.
Published: (2024-01-01)

Actoprotective activity of 6-monosubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino-[2,3-c]quinazoline-2-ones
by: O. S. Kolomoets, et al.
Published: (2016-12-01)

Acute toxicity of 3-(2-, 3-fluorophenyl)-6-(aryl-, hetaryl)-[1,2,4]triazole[3,4-b][1,3,4]thiadiazoles
by: O. A. Bihdan, et al.
Published: (2017-12-01)

The study of UV-spectra of the sodium (3-oxo-3,4-dihydro-2H-[1,2,4]triazino[4,3-c]quinazolin-4-yl)acetate
by: О. V. Kryvoshey
Published: (2016-04-01)

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines
by: Ye. O. Karpun, et al.
Published: (2020-11-01)

A study of antimicrobial and antifungal activity of 2-((5-(2-bromophenyl)-4-substituted-4H-1,2,4-triazol-3-yl)thio)acetates
by: A. A. Safonov, et al.
Published: (2020-11-01)

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles
by: A. A. Safonov, et al.
Published: (2022-12-01)

Study of the antimicrobial activity of new quinazoline derivatives against <i>Staphylococcus aureus</i>
by: M. A. Samotrueva, et al.
Published: (2025-07-01)

Time-kill properties of citrus peel essential oils and constituents against foodborne pathogens
by: Lee Je-Hyuk
Published: (2025-06-01)

The study of analgesic effect of 5-(furan-2-yl, 2-methylfuran-3-yl)-4-amino-1,2,4-triazole-3-thion derivatives
by: D. M. Danilchenko
Published: (2018-10-01)

Antiradical activity of novel 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives
by: A. A. Safonov, et al.
Published: (2021-07-01)

Purposeful search and characteristic of anti-inflammatory activity of sodium (3-R-2-оxo-2Н-[1,2,4]triazino[2,3-c]quinazolin-6-yl)alkylcarboxylates and their halogen containing analogues
by: V. V. Yakubovska, et al.
Published: (2016-04-01)

SYNTHESIS AND ANTIOXIDANT ACTIVITY OF (E)-3-(3-(4-OXO-4H-CHROMEN-3-YL)ACRYLOYL) 2H-CHROMEN-2-ONE DERIVATIVES
by: S. S. Shatokhin, et al.
Published: (2021-10-01)

Synthesis, Cytotoxicity, Xanthine Oxidase Inhibition, Antioxidant of New Pyrazolo{3,4 d}Pyrimidine Derivatives
by: Khammas et al.
Published: (2019-12-01)

Actoprotective activity research of 2-((5-(2-bromophenyl)-4-substituted-4H-1,2,4-triazole-3-yl)thio)acetates
by: A. A. Safonov, et al.
Published: (2020-09-01)

Substituted pyrrolo[1,2-a][1,2,4]triazolo-(triazino-)[c]quinazolines - a promising class of lipoxygenase inhibitors
by: V. V. Stavytskyi, et al.
Published: (2020-05-01)

Overcoming the protective functions of macrophages by Streptococcus pyogenes virulence factors
by: I. S. Freydlin, et al.
Published: (2019-05-01)

Studies on the method of controlling enzymatic reaction time of acetylene reduction in determining associative nitrogenase activity of associative system
by: JI Tian-wei, et al.
Published: (2003-07-01)

Synthesis and anticancer activity of 2-cyano-2-(4-oxo-3-phenylthiazolidin-2-ylidene)-N-arylacetamides
by: A. P. Kryshchyshyn-Dylevych
Published: (2020-08-01)

Antihypoxic activity of benzylidenhydrazides of 4-R-5- (thiophene-2-ylmethyl)-1,2,4-triazol-3-il)thioacetic acid
by: O. A. Suhak, et al.
Published: (2017-08-01)

The study of the optical activity of some S-derivatives 4-R-5-((((3-(pyridin-4-yl)-1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1, 2,4-triazole-3-thiols
by: Ye. O. Karpun, et al.
Published: (2022-08-01)

Anti-tuberculosis activity research of 5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol
by: A. A. Safonov, et al.
Published: (2019-12-01)

Assessment of Antimycobacterial Activity of Newly Synthesized Pyrimidine Derivatives Against Mycobacterium tuberculosis
by: M. A. Samotrueva, et al.
Published: (2022-08-01)

Evaluation of hepatotoxic properties of pyrimidine derivatives
by: A. L. Yasenyavskaya, et al.
Published: (2022-06-01)

Actoprotective activity of 5-(2-bromophenyl)-4-amino-4H-1,2,4-triazole-3-thione and its S-derivatives
by: Ye. S. Pruglo
Published: (2016-04-01)

Synthesis, Characterization, and Biological Evaluation of Some 3<i>d</i> Metal Complexes with 2-Benzoylpyridine 4-Allylthiosemicarbazone
by: Vasilii Graur, et al.
Published: (2025-07-01)

Impact of Hyperbaric Oxygenation on Blood Anticolibacillary Activity in Hepatectomy
by: P. N. Savilov, et al.
Published: (2007-12-01)

The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis.
by: S. N. Krutikov, et al.
Published: (2014-06-01)