Catalyst-Free Spontaneous Aza-Mannich/Lactamization Cascade Reaction: Easy Access to Polycyclic δ-Lactams

Ring-fused azacyclic compounds are important building blocks in the synthesis of natural products and pharmaceutical agents. Herein, we report an effective and valuable one-pot approach to obtaining polycyclic fused δ-lactams from readily available 2-formylphenyl acetate and diamines under catalyst-...

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Bibliographic Details
Main Authors: Antonia Di Mola, Caterina Vietri, Consiglia Tedesco, Antonio Massa
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/13/2702
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