THE ROLE OF RIOCIGUAT IN THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONNECTIVE TISSUE DISEASE

Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). Binding NO with sGC - enzyme catalyzes the synthesis of a signal molecule of cyclic guanosine monophosphate (cGMP), which plays an important role in the regulation of processes that affect vascular to...

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Bibliographic Details
Main Authors: O. Ya. Vasiltseva, K. I. Ivanov, E. A. Devetyarova, O. E. Yakovleva
Format: Article
Language:Russian
Published: InterMedservice 2019-12-01
Series:Евразийский Кардиологический Журнал
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Online Access:https://www.heartj.asia/jour/article/view/346
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