Structural insights into human polyspecific organic anion transporters OAT1 and OAT4
Summary: Organic anion transporters (OATs) play a critical role in the transport of organic anions. OAT1, located in the kidney, is essential for the transport of organic anion drugs and metabolites, while OAT4 facilitates absorption processes in the kidney and placenta. Here, we resolved the cryo-e...
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Main Authors: | Wei Zhang, Youfu Chu, Ziyang Shan, Huihui Liu, Xuemei Yang, Jing Nan, Feiwen Wei, Yanqing Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-07-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725007466 |
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