Structural insights into human polyspecific organic anion transporters OAT1 and OAT4

Summary: Organic anion transporters (OATs) play a critical role in the transport of organic anions. OAT1, located in the kidney, is essential for the transport of organic anion drugs and metabolites, while OAT4 facilitates absorption processes in the kidney and placenta. Here, we resolved the cryo-e...

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Bibliographic Details
Main Authors: Wei Zhang, Youfu Chu, Ziyang Shan, Huihui Liu, Xuemei Yang, Jing Nan, Feiwen Wei, Yanqing Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007466
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