EvoNB: A protein language model-based workflow for nanobody mutation prediction and optimization

The identification and optimization of mutations in nanobodies are crucial for enhancing their therapeutic potential in disease prevention and control. However, this process is often complex and time-consuming, which limit its widespread application in practice. In this study, we developed a workflo...

Full description

Saved in:
Bibliographic Details
Main Authors: Danyang Xiong, Yongfan Ming, Yuting Li, Shuhan Li, Kexin Chen, Jinfeng Liu, Lili Duan, Honglin Li, Min Li, Xiao He
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177925000772
Tags: Add Tag
No Tags, Be the first to tag this record!