PTEN: A potential prognostic marker in virus-induced hepatocellular carcinoma

PTEN is the second most frequently mutated tumor suppresser gene in cancers after p53. Genetic and epigenetic alterations in the PTEN gene and its regulatory regions have been reported in various studies. PTEN is a crucial downregulator of the pro-survival phosphoinositide 3-kinase/Akt/mammalian tar...

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Bibliographic Details
Main Authors: Ayesha Khalid, Tabinda Hussain, Sobia Manzoor, Muhammad Saalim, Saba Khaliq
Format: Article
Language:English
Published: SAGE Publishing 2017-05-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705754
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