Opportunities for and Challenges of Conducting Indirect Treatment Comparisons and Meta-Analyses for Vaccines in Post-EU HTA Regulation Era

QR Code

Opportunities for and Challenges of Conducting Indirect Treatment Comparisons and Meta-Analyses for Vaccines in Post-EU HTA Regulation Era

The dynamic nature of infectious diseases introduces inherent challenges to the design of vaccine clinical trials, which consequently makes vaccine indirect treatment comparisons (ITCs) and meta-analyses (MAs) more challenging compared with regular pharmaceuticals. However, comparisons of efficacy a...

Full description

Saved in:

Bibliographic Details
Main Authors:	Charlotte Graham, Erin Barker, Joe Moss, Emily Gregg, Rachael McCool, Nathalie Largeron, Mélanie Trichard, José Bartelt-Hofer, Maribel Tribaldos
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Journal of Market Access & Health Policy
Subjects:	indirect treatment comparison meta-analysis comparative effectiveness vaccine health technology assessment EU Regulation on Health Technology Assessment
Online Access:	https://www.mdpi.com/2001-6689/13/2/31
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Using indirect comparisons in pharmacoeconomic examination
by: Yu. E. Balykina, et al.
Published: (2015-03-01)

INDIRECT COMPARISONS IN HEALTH TECHNOLOGY ASSESSMENT
by: S. V. Goryajnov, et al.
Published: (2012-04-01)

COMPARATIVE CHARACTERISTICS OF THE EFFECTIVENESS OF DIRECT AND INDIRECT RESTORATIONS ON TEETH WITH DISCOLORATION
by: I.V. Zhyvotovskyi, et al.
Published: (2019-09-01)

Evaluation of Bioequivalence of Generic Imatinib Products and Generic Tacrolimus Products Based on Indirect Comparison of the Results of Their Bioequivalence Studies
by: D. V. Goryachev, et al.
Published: (2019-09-01)

THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS
by: Sh. F. Erdes
Published: (2016-12-01)

HTA CORE MODEL
by: R. I. Yagudina, et al.
Published: (2015-03-01)

Cost of epilepsy in the Russian Federation
by: A. S. Romanov, et al.
Published: (2024-10-01)

Enhancing Patient Engagement in HTA: Using Consensus Research to Overcome PICO Scoping Challenges Under the EU HTAR
by: Emanuele Arcà, et al.
Published: (2025-06-01)

EFFICACY AND SAFETY OF THE ORAL ANTICOAGULANTS IN THE MANAGEMENT OF VENOUS THROMBOEMBOLISM: INDIRECT COMPARISON
by: V. I. Petrov, et al.
Published: (2016-12-01)

Matching-adjusted indirect comparison between garadacimab and lanadelumab for the long-term prophylactic treatment of patients with hereditary angioedema
by: Sarah Walsh, et al.
Published: (2025-07-01)

THE ANALYSIS OF METHODOLOGIC CHARACTERISTICS OF RESEARCHES ON SOCIAL AND ECONOMIC BURDEN OF DISEASES IN RUSSIA IN THE FRAMES OF DEVELOPMENT OF STANDARD COST OF ILLNESS METHODOLOGY FOR THE HEALTH TECHNOLOGY ASSESSMENT
by: V. I. Ignatyeva, et al.
Published: (2015-03-01)

Hazards : technology and fairness /
Published: (1986)

THE STYLISTIC ROLE OF DETERMINOLOGISMS IN THE COMPOSITION OF COMPARISONS (based on Bohdan Lepky`s story “Motrya”)
by: Zoriana J. Kunch.
Published: (2023-05-01)

Approaches to resolve practical challenges in the context of assessing the price of biosimilar products
by: A. H.-M. Valeeva, et al.
Published: (2025-01-01)

RESULTS OF EVALUATING THE EFFICACY OF SECUKINUMAB VERSUS ADALIMUMAB IN TREATING PSORIATIC ARTHRITIS BY USING THE MATCHING-ADJUSTED INDIRECT COMPARISON METHOD
by: T. V. Korotaeva
Published: (2016-12-01)

Approaches for Health Technology Assessment in Europe: Situational Analysis
by: Slaveyko Djambazov, et al.
Published: (2016-12-01)

Towards the Operationalization of Health Technology Sustainability Assessment and the Early Eco Design of the Internet of Medical Things
by: Ernesto Quisbert-Trujillo, et al.
Published: (2025-06-01)

Comparison of several alternative uses of targeted antirheumatic drugs in monotherapy for early rheumatoid arthritis
by: O. V. Shatalova, et al.
Published: (2017-04-01)

Society, technology, and risk assessment /
Published: (1980)

Review of methods for assessing the cost-effectiveness of medical interventions
by: T. I. Busheva, et al.
Published: (2025-01-01)

The economic evaluation of a vaccination against pertussis infection in children in Moscow
by: S. V. Svetlichnaya, et al.
Published: (2023-10-01)

Judicial claims for access to treatment in the private health insurance sector in Brazil
by: Daniel Wei Liang Wang, et al.

Review of the current approaches to the assessment of the drug innovative potential worldwide
by: N. Z. Musina, et al.
Published: (2017-11-01)

Indirect protection from rotavirus vaccines: a systematic review
by: Tyler Chavers, et al.
Published: (2024-12-01)

Strengthening the EU Health Technology Assessment Regulation: Integrating National Immunization Technical Advisory Groups for Comprehensive Vaccine Assessments
by: Jasmijn Beekman, et al.
Published: (2025-04-01)

How should medicines reimbursement work? The views of Spanish experts
by: Juan Carlos Rejon-Parrilla, et al.

A Guidebook for technology assessment and impact analysis
Published: (1980)

Choosing the optimal method of stock assessment for Saccharina japonica in the northwestern Tatar Strait
by: A. A. Dulenin, et al.
Published: (2022-07-01)

THE METHODOLOGY FOR ASSESSING THE COMPETITIVENESS OF PUBLIC CATERING ENTERPRISES
by: T. V. Shchedrina, et al.
Published: (2022-08-01)

The Effects of (Dis)similarities Between the Creator and the Assessor on Assessing Creativity: A Comparison of Humans and LLMs
by: Martin op ‘t Hof, et al.
Published: (2025-07-01)

Economics of diabetes mellitus type 2 control based on big data modeling
by: S. V. Svetlichnaya, et al.
Published: (2024-04-01)

Modern needs in health technology assessment: a study of comparative effectiveness
by: A. V. Pavlysh, et al.
Published: (2013-04-01)

The health technology assessment system in Australia
by: V. V. Omelyanovskiy, et al.
Published: (2020-02-01)

Surrogate endpoints in cost-effectiveness analysis for use in medical technology assessment
by: T. I. Busheva, et al.
Published: (2025-07-01)

Evaluation of the economic efficacy of vaccination against pertussis based on real-world data
by: S. V. Svetlichnaya, et al.
Published: (2023-03-01)

Introduction of medical products into healthcare practice and costs reimbursement: European experience
by: V. V. Omelyanovsky, et al.
Published: (2018-08-01)

PRINCIPLES OF IMPORT SUBSTITUTION REGARDING DRUGS
by: Alana Viktorovna Dzaneva, et al.
Published: (2015-09-01)

The structure of an online assessment of science and social studies content: testing optional formats of a general outcome measure
by: Paul Mooney, et al.
Published: (2014-06-01)

Landslide Risk Assessment as a Reference for Disaster Prevention and Mitigation: A Case Study of the Renhe District, Panzhihua City, China
by: Yimeng Zhou, et al.
Published: (2025-06-01)

Well-Being As a Component Of Subjective Health Assessment In Students
by: O. B. Polyakova, et al.
Published: (2024-11-01)